UPDATED PROTOCOL OF THE SANO TRIAL: A STEPPED-WEDGE CLUSTER RANDOMISED TRIAL COMPARING SURGERY WITH ACTIVE SURVEILLANCE AFTER NEOADJUVANT CHEMORADIOTHERAPY FOR OESOPHAGEAL CANCER

Abstract Background The Surgery As Needed for Oesophageal cancer (SANO) Horse Poll Pads trial compares active surveillance with standard oesophagectomy for patients with a clinically complete response (cCR) to neoadjuvant chemoradiotherapy.The last patient with a clinically complete response is expected to be included in May 2021.The purpose of thi

Reliable access to electricity is still a challenge in many developing countries.Indeed, rural areas in sub-Saharan Africa and developing countries such as India still encounter frequent power outages.Local energy markets (LEMs) have emerged as a low-cost solution enabling prosumers with power supply systems such as solar PV to sell their surplus o

The Calendar complete mitogenome of the Atlantic spiny lumpsucker (Eumicrotremus spinosus) was generated using the PacBio Sequel II HiFi sequencing platform.The mitogenome assembly has a length of 19,281 bp and contains 13 protein-coding sequences, 22 tRNA genes, 2 rRNA genes, one control region containing the D-loop (2383 bp) and a duplicate contr

The Covid-19 pandemic has seen the emergence of various vaccines being produced at an unprecedented speed.It is not surprising that new adverse events to these vaccines are still being reported and Immune thrombocytopenic Purpura [ITP] happens to be one among them.Moderna and copyright vaccine have been linked to it.Association of ITP with SARS-CoV